‘The Human Genome Project’ – A Cosmic Joke that has Scientists Rolling in the Aisle

Conclusion on….the Cosmic Joke?

The results of the Genome project reveal that there are only about 34,000 genes in the human genome. Two thirds of the anticipated genes do not exist! How can we account for the complexity of a genetically-controlled human when there are not even enough genes to code just for the proteins?

More humiliating to the dogma of our belief in genetic determinacy is the fact that there is not much difference in the total number of genes found in humans and those found in primitive organisms populating the planet. Recently, biologists completed mapping the genomes of two of the most studied animal models in genetic research, the fruit fly and a microscopic roundworm (Caenorhabditis elegans).

The primitive Caenorhabditis worm serves as a perfect model to study the role of genes in development and behavior. This rapidly growing and reproducing primitive organism has a precisely patterned body comprised of exactly 969 cells, a simple brain of about 302 ordered cells, it expresses a unique repertoire of behaviors, and most importantly, it is amenable to genetic experimentation. The Caenorhabditis genome is comprised of over 18,000 genes. The 50+ trillion-celled human body has a genome with only 15,000 more genes than the lowly, spineless, microscopic roundworm.

Obviously, the complexity of organisms is not reflected in the complexity of its genes. For example the fruit fly genome was recently defined to consist of 13,000 genes. The eye of the fruit fly is comprised of more cells than are found in the entire Caenorhabditis worm. Profoundly more complex in structure and behavior than the microscopic roundworm, the fruit fly has 5000 fewer genes!!

The Human Genome Project was a global effort dedicated to deciphering the human genetic code. It was thought the completed human blueprint would provide science with all the necessary information to “cure” all of mankind’s ills. It was further assumed that an awareness of the human genetic code mechanism would enable scientists to create a Mozart or another Einstein.

The “failure” of the genome results to conform to our expectations reveals that our expectations of how biology “works” are clearly based upon incorrect assumptions or information. Our “belief” in the concept of genetic determinism is fundamentally…flawed! We can not truly attribute the character of our lives to be the consequence of genetic “programming.” The genome results force us to reconsider the question: “From whence do we acquire our biological complexity?”

In a commentary on the surprising results of the Human Genome study, David Baltimore, one of the world’s most prominent geneticists and Nobel prize winner, addressed this issue of complexity:

“But unless the human genome contains a lot of genes that are opaque to our computers, it is clear that we do not gain our undoubted complexity over worms and plants by using more genes. Understanding what does give us our complexity-our enormous behavioral repertoire, ability to produce conscious action, remarkable physical coordination, precisely tuned alterations in response to external variations of the environment, learning, memory…need I go on?-remains a challenge for the future.” (Nature 409:816, 2001)

Scientists have continuously touted that our biological fates are written in our genes. In the face of that belief, the Universe humors us with a cosmic joke: The “control” of life is not in the genes. Of course the most interesting consequence of the project’s results is that we must now face that “challenge for the future” Baltimore alluded to. What does “control” our biology, if not the genes?

Over the last number of years, science and the press’ emphasis on the “power” of genes has overshadowed the brilliant work of many biologists that reveal a radically different understanding concerning organismal expression. Emerging at the cutting edge of cell science is the recognition that the environment, and more specifically, our perception of the environment, directly controls our behavior and gene activity.

The molecular mechanisms by which animals, from single cells to humans, respond to environmental stimuli and activate appropriate physiological and behavioral responses have recently been identified. Cells utilize these mechanisms in order to dynamically “adapt” their structure and function to accommodate ever-changing environmental demands. The process of adaptation is mediated by the cell membrane (the skin of the cell), which serves as the equivalent of the cell’s “brain.” Cell membranes recognize environmental “signals” through the activity of receptor proteins. Receptors recognize both physical (e.g., chemicals, ions) and energetic (e.g., electromagnetic, scalar forces) signals.

Environmental signals “activate” receptor proteins causing them to bind with complementary effector proteins. Effector proteins are “switches” that control the cell’s behavior. Receptor-effector proteins provide the cell with awareness through physical sensation. By strict definition, these membrane protein complexes represent molecular units of perception. These membrane perception molecules also control gene transcription (the turning on and off of gene programs) and have recently been linked to adaptive mutations (genetic alterations that rewrite the DNAcode in response to stress).

The cell membrane is a structural and functional homologue (equivalent) of a computer chip, while the nucleus represents a read-write hard disk loaded with genetic programs. Organismal evolution, resulting from increasing the number of membrane perception units, would be modeled using fractal geometry. Reiterated fractal patterns enable a cross-referencing of structure and function among three levels of biological organization: the cell, the multicellular organism and societal evolution. Through fractal mathematics we are provided with valuable insight into the past and future of evolution.

The environment, through the act of perception, controls behavior, gene activity and even the rewriting of the genetic code. Cells “learn” (evolve) by creating new perception proteins in response to novel environmental experiences. “Learned” perceptions, especially those derived from indirect experiences (e.g., parental, peer and academic education), may be based upon incorrect information or faulty interpretations. Since they may or may not be “true,” perceptions are in reality-beliefs!

Our new scientific knowledge is returning to an ancient awareness of the power of belief. Beliefs are indeed powerful…whether they are true or false. While we have always heard of the “power of positive thinking,” the problem is negative thinking is just as powerful, though in the “opposite” direction. Problems encountered in health and in the unfolding of our lives are generally connected to the “misperceptions” acquired in our learning experiences. The wonderful part of the story is that perceptions can be relearned! We can reshape our lives in retraining our consciousness. This is a reflection of the ageless wisdom that has been passed down to us and is now being recognized in cellular biology.

An understanding of the newly described cell-control mechanisms will cause as profound a shift in biological belief as the quantum revolution caused in physics. The strength of the emerging new biological model is that it unifies the basic philosophies of conventional medicine, complementary medicine and spiritual healing.


9 thoughts on “‘The Human Genome Project’ – A Cosmic Joke that has Scientists Rolling in the Aisle

  1. A large one. Suggests thinking of new dimensions. Your words are like seeds of new forms. Breaking the crust of the archetypal cocoon. It smells like a metamorphosis of marionettes Thanks :)~

  2. I love your articles sir.
    I understand the power of basics.
    If you want the simplest answer for your question, ” USER ”
    But what makes the difference between the users?
    so … it ends with searching for the meaning of life. and the answer is …why? ends with ….it is so!!!! natural, God made. God only knows….it ends there. And then who is God and then that advaita, dvaita and vishishtadvaita philosophy concerning the relationship/existence of individual soul and universal soul.
    Can our scientific methods get us the answer. No…..but why should we try…
    the byproducts of such search makes life more exciting….everlasting excitement called life…..and it is cyclical
    the tree or the seed.
    Logic…. seed….because that is our experience…. we have evolved from the seed. Theory of genesis and evolution….seed first. But who wrote the growth code in the seeds? Boss God only knows and it is no wonder that our seers made the search of God the highest purpose of our life and they defined that state of seeking
    as enlightenment ” everlasting bliss ” !! from abysmal suffering to everlasting bliss….the journey of life….
    The opposite pole is futility…oh! God, Make me non existent. The equilibrium is experiencing both the struggle… suffering and bliss for they is no perception of the one without the other….yin and yaang philosophy.
    Philosophy is the food for thought. What do you say sir and where from such philosophy originated….
    God only knows!!!! so the moral is …there is no meaning, but the search for the meaning makes the life exciting!!!!
    Some how such thoughts would make me a mystic and stop further research…
    No doubt the degree is called doctor of philosophy!!!!
    So as a first step, I will have to prove the user is the boss till he becomes aware of his powers and that awareness is called ” enlightenment ” Thank you boss.
    I had a clinical story about the microscopic round worm…my version…. It happened to be strongoiloides stercorlis larvae hatched freshly in the stools being examined!!!! I told the surgeon and they never want to show they are ignorant!!!! he thought I saw a round worm under the microscope and ordered ” Piperazine citrate ” a drug for round worm. He would not know more than that and I was not in a position to teach him what I knew but he was reluctant to learn from his student!!!! To tell you the truth, I had seen those larvae first time and after several years, it struck to me they were strongyloides stercoralis and thiabendazole was the =treatment of choice. I knew that theoretically and I became aware of that after seeing! The patient had chronic abdominal pain and provisionally diagnosed as chronic appendicitis and posted for observation and surgery. Funny life.

  3. There is another aspect which has gone unspoken. Many scientific endeavors are filled with tall promises in order to get funding. Part of the sense of failure comes with the expectation of miracles wrought by man. Shall we then stop scientific enquiry due to this systemic flaw? It seems not, as each “failure” does bring us nearer to another truth.

  4. Siento que nos han enseñado a usar nuestras mentes de manera primitiva sin evaluar lo que esta puede llegar a hacer cuando está profundamente conectada al amor. El latido de nuestro corazón debe estar sereno, asi, latidos o pulsos, mente, amor, logran la evolusión. No es la razón lo que creíamos que era, no es el análisis, es la certeza, la serenidad y el amor por el objetivo que se persigue. Esta siento que es la verdadera evolución. Capas de modificar, células, tejidos, maneras de comunicarnos. Claro que todo esto va a dejar fuera todo el sistema hasta ahora conocido. Con entrenamiento podemos ver la energía a traves de nuestros ojos físicos, desenfocando en ves de enfocar… Podemos verla con nuestros ojos físicos y también con los mentales. La conciencia de saber que podemos hacerlo cambia todo, todo. El verdadero problema es el tiempo que llevará al ser humano separarse de su ego y sus bienes materiales y que entienda que no habrá en un futuro hombres mas poderosos que otros, claro que lamentablemente la naturaleza hará como siempre ha hecho su selección natural, pero esta ves no basándose en los más fuertes de su especie, sino en los más aptos para este nuevo mundo

  5. The author is trying to explain, and doing it rather well – though in almost every phrase one senses his fight against that human tendency to fall back onto causal thinking, or the instinctive need to glorify our own existence. The sub-headline “become a master of your life” is the saddest sentence of the essay. Excuse me ??

    It ain’t easy – we possess no straight way to reason, always having to fight against, around the subconscious tendencies that are immanent to our brains. How could it be different ?
    Just view the comments and stand in awe of the limits to our logic, barely able to interpret and accept interesting findings in a rational way.

    In the end, we have evolved into highly delusional rather than intelligent animals, condemned to mis-take a certain spectre of reality for the ‘world’, urgently simplifying everything new and seemingly mysterious to fit our infantile expectations.

    God done it – so cool. There’s hope that artificial intelligence might enable us to take a giant step past this sad, single-minded sandpit of our biological limits, but then our supposedly brightest minds (Hawking, Musk and consorts) have already been mouthing their animal fear of exactly that happening.

  6. Ok … If You want and like to Believe and/or store Beliefs that is on “the package of free services”, path and choices ..
    But For Existence, To Believe is not require …
    There are an spectrum of Realization more extensive when there are not attachments to beliefs … Beliefs becomes just conventions to provide services by cultural biases on humans … The existence do not require beliefs but must be dispose of those when the environment is deployed around the side-effects from “the beliefs” …

    One thing that tends to merge when the existence scan the organism-environment and the environment to find the immediate effects of Beliefs is that the organism-environments that are build around those conceptual-cultural-social structures deploy a kind of inner “Castle of Cards” for the Self … and the general social experience becomes on How they observe and project that “Castle of Cards” and the stages to set the conventions for the Games …

    Then, Imagine that you don’t require a “Castle of Cards” …

    What happens???

    Nothing … The stage is the same … but now, you know what to do with The Cards … and not The Hand controls who you are … you can enter and go out of the stages … and more fun, you discover (without Beliefs, real experience) that the casino is just an Infinitesimal tiny place on The Cosmos …

    … but The People with addiction to the Casino tends to Fear a Lot to lost the Castle of Cards … They are playing to lost … because Death always take The Cards … But If you don’t require cards and do not have cards …Death can not take something to You …. There are not a Castle of Cards for destroy … There are not a Self to send to Eternal Oblivion …

    When To Believe is not require … You can be inside the casino playing Cards as a “Magician with The Best Hands of the Season” and If death knocks the doors of the heart to play the last game … You dance and enjoy The Game …

    To Believe is not require …

    but you are Free to choice to believe on whatever …

    That is “Your” issue, not “Mine” …

    Existence is without Believers …

  7. Pingback: ‘The Human Genome Project’ – A Cosmic Joke that has Scientists Rolling in the Aislehe recognition that the environment, and more specifically, our perception of the environment, directly controls our behavior and gene activity « Tc

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