Ever heard that a “change in diet, exercise may change your genes”? Here’s the study!

Change in Diet, Exercise may Change your Genes

Study: After 3 months, lifestyle changes made a difference in 500 genes

WASHINGTON – Comprehensive lifestyle changes including a better diet and more exercise can lead not only to a better physique, but also to swift and dramatic changes at the genetic level, U.S. researchers said on Monday.

In a small study, the researchers tracked 30 men with low-risk prostate cancer who decided against conventional medical treatment such as surgery and radiation or hormone therapy.

The men underwent three months of major lifestyle changes, including eating a diet rich in fruits, vegetables, whole grains, legumes and soy products, moderate exercise such as walking for half an hour a day, and an hour of daily stress management methods such as meditation.

As expected, they lost weight, lowered their blood pressure and saw other health improvements. But the researchers found more profound changes when they compared prostate biopsies taken before and after the lifestyle changes.

‘’After the three months, the men had changes in activity in about 500 genes — including 48 that were turned on and 453 genes that were turned off.

‘It’s all in my genes, what can I do?’ 
The activity of disease-preventing genes increased while a number of disease-promoting genes, including those involved in prostate cancer and breast cancer, shut down, according to the study published in the journal Proceedings of the National Academy of Sciences.

The research was led by Dr. Dean Ornish, head of the Preventive Medicine Research Institute in Sausalito, California, and a well-known author advocating lifestyle changes to improve health.

“It’s an exciting finding because so often people say, ’Oh, it’s all in my genes, what can I do?’ Well, it turns out you may be able to do a lot,” Ornish, who is also affiliated with the University of California, San Francisco, said in a telephone interview.

“’In just three months, I can change hundreds of my genes simply by changing what I eat and how I live?’ That’s pretty exciting,” Ornish said. “The implications of our study are not limited to men with prostate cancer.”

Ornish said the men avoided conventional medical treatment for prostate cancer for reasons separate from the study. But in making that decision, they allowed the researchers to look at biopsies in people with cancer before and after lifestyle changes.

“It gave us the opportunity to have an ethical reason for doing repeat biopsies in just a three-month period because they needed that anyway to look at their clinical changes (in their prostate cancer),” Ornish said.

Reuters:  updated 3:23 p.m. PT, Mon., June. 16, 2008.

http://www.ncbi.nlm.nih.gov/pubmed/18559852

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18 thoughts on “Ever heard that a “change in diet, exercise may change your genes”? Here’s the study!

  1. Wow! I love this research. It’s empowering. Do you have blogs that you are subscribed to that you would be willing to share with me? I would like more outlets for learning. Thank you for posting!!!! Xox

  2. Reblogged this on rectalcancermyass and commented:
    Dr. Bruce Lipton has been studying and teaching about genes and how we DO have control over them. We can no longer blame our parents for inheriting their genes for whatever health issues we have.

    I am not my parent’s genes. I do not have to get the same health problems they have and neither do you.

    Be well!
    Ingebird

  3. Pingback: Change your lifestyle, change your genes – the power is in you! | Bio-Sil South Africa

    • Cells breathe? I don’t believe this is just a theory. I learned as a student nurse in the late 1940s that every cell in the body has the following abilities: respiration, digestion, elimination and reproduction. I don’t know if changes in genes is what I am experiencing, but I am still making progress as one recovering from a stroke. Prognosis was nil. I should be dead or, at best a vegetable. Instead, after 2 1/2 years I walk with a walker, do many exercises unaided, and am very active. Johanna, stay positive and listen to your body. Love and blessings, Rowena

  4. Can these changes in genes be seen in muscular dystrophy patients also? If by any way their condition can get better. Plz do reply.

  5. Pingback: Journal of Lifestyle Medicine Calendar Podcast for 3/18/15 | Sorgatron Media

  6. Pingback: 3 Simple But Effective Tricks To Keep Exercising | Morgan Isaac Health and Wellness

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